Product Introduction
Melanotan 2 ( MT2 Peptide ) is a powerful synthetic cyclic peptide analogue of the alpha-melanocyte stimulating hormone ( α-MSH ); a naturally occurring polypeptides. MT2 is designed by introducing a cyclic molecular structure that holds improved biological stability, greater half-life and higher receptor binding affinity than the endogenous α-MSH. Primarily acting on melanocortin receptors in various human tissues, this research-grade peptide has been shown to modulate melanin production with antioxidant and anti-inflammatory mechanisms. MT2 peptide is provided in high-purity lyophilized powder for research use only, offering consistent solubility, stable batch-to-batch consistency and reproducible pharmacological activity. Internationally, it is well recognised as a key experimental reagent in the study of pigmentation, immunological regulation, oxidative stress research and preclinical physiology mechanism exploration.
Product Research Background
MT2 Peptide was developed from academic studies in the 1980s and 1990s aimed to address the extremely poor stability and short half-life of native α-MSH. In vivo natural melanocyte-stimulating hormone degradation occurs rapidly which greatly limits its experimental and clinical research value. In 1995, scientists designed a cyclic Melanotan 2 analog with optimized peptide chain structure to solve the instability shortcomings of natural MSH [24]. The strong activation effect of enemas on melanocortin receptors, its potential in the immune response and anti-oxidation were all successfully verified by preclinical studies early. Originally developed for the treatment of skin pigmentation disorders, commercialization of MT2 was halted after a tactical shift in clinical trial strategy [9]. Nonetheless, it has continued to be used and investigated in academic laboratories amassing vast authoritative experimental data making it one of the most classical peptide in melanocortin targeting research.
Compliance & Research Disclaimer
This MT2 Peptide is for research use only. An investigational product is not a licensed pharmaceutical but neither has it been approved for clinical use by, say, the FDA or EMA or other regional medical regulatory authority. This product cannot be used for human clinical diagnosis, treatment of human diseases, subcutaneous injection, oral administration or any commercial off-label use. Disclaimer: The content of all product descriptions and experimental data reports are for academic research reference only, and cannot replace any medical advice or treatment claims. Purchases and research: All purchasers, along with researchers, must comply with applicable local laws, institutional lab management and ethical guidelines. We take no responsibility for typical illegal uses, unruly usage or any use of the product that is not research related.
Laboratory Applications
MT2 Peptide has significant and irreplaceable value on applications in modern biomedicine laboratories. First, it is an important reagent for skin pigmentation mechanism studies and has been used in many in vitro melanocyte cell experiments or animal model experiments to study the mechanistic insights on melanin synthesis, pigment deposition and human photoprotection of skin. The second contribution to this field as of the break that it promotes immunological and inflammatory investigations assisting scientists in examining how melanocortin receptor activation regulates systemic inflammation and immune cell function. Finally, to investigate the protective effect of drugs on cellular oxidative damage under oxidative stress and metabolic regulation in experiments. Furthermore, MT2 is widely used for comparisons of ligand activity for different subtypes of melanocortin receptor as well confirmation of pharmacological mechanism as well safety evaluation in preclinical studies, giving precise and reproducible experimental data for biomedical investigations.
Quality Standards
MT2 Peptide obtainmentsOur research-grade MT2 Peptide follows strict international specifications for synthetic peptide production and laboratory reagent quality. Utilizing cutting-edge solid-phase peptide synthesis (SPPS) technology, it contains a whole and pure cyclic amino acid sequence without structure deviations. With the involvement of high-performance liquid chromatography (HPLC) in addition to each production batch, guaranteed purity ≥98% and defined resolution of synthesis residues, impurity fragments and heavy metal contaminants. Mass spectrometry (MS) detection is performed in a batch-wise manner to confirm molecular weight and the integrity of component structural components. The product uses vacuum lyophilized sealed packaging to prevent oxidation and activity subsidence, is manufactured in GMP-standard clean posts. All products undergo stringent endotoxin screening against contaminated contamination limits and tests on long-term stability, with governing dossier of batch-specific COA quality evaluation records presented alongside each new order.
Frequently Asked Questions (FAQs)
Question 1: What are the primary research benefits of MT2 Peptide?
A1: A Stable Cyclic Structure, High Melanocortin Receptor Affinity and Longer Biological Half-life than Natural α-MSH. This reagent with stable experimental effects and repeatable data is the preferred reagent for pigmentation and melanocortin regulation studies.
Q2: What is the storage requirement of MT2 peptide?
Answer: MT2 lyophilized powder should be tightly sealed and stored in freeze, -20°C in a dry, dark and steril conditions. It should be repeatedly frozen and thawed. It is recommended to use the reconstituted peptide solution a.s.a.p. after you've made it, in order to avoid losing bioactivity of the peptide.
Q3: Is MT2 suitable for both in vitro and in vivo laboratory experiments?
A3: Yes. High-purity MT2 peptide with ultra-low endotoxin, high water-solubility and stable biological activity, suitable for in vitro cell experiments and in vivo animal model studies.
Q4: Is it possible for humans to use MT2 peptide for tanning or medical treatment?
A4: No. This is only a professional laboratory research reagent, not a cosmetic or pharmaceutical product. Use as a tanning or medical treatment on any human body is strictly prohibited.
10 Common FAQs About Peptides
- What is a peptide?
Answer: A peptide is a short chain of amino acids linked together by peptide bonds. It is smaller and more easily absorbed by the human body than proteins, serving as a fundamental functional substance in biological organisms.
- What is the difference between peptides and proteins?
Answer: The core difference lies in molecular length and structure. Peptides are short amino acid chains (usually consisting of 2–50 amino acids), while proteins are long, complex amino acid chains with stable three-dimensional structures. Peptides have stronger permeability and faster absorption efficiency than proteins.
- What are the main types of peptides?
Answer: Peptides are mainly classified by the number of amino acids: dipeptides, tripeptides, oligopeptides (2–10 amino acids) and polypeptides (10–50 amino acids). They can also be divided into natural peptides and synthetic peptides according to their sources.
- What are the biological functions of peptides?
Answer: Peptides have diverse biological activities, including regulating human metabolism, improving immune function, promoting cell repair, anti-oxidation, anti-aging, and adjusting hormone levels. They act as key signaling molecules and regulatory factors in the body.
- Are peptides safe for human use?
Answer: Most natural and medically approved synthetic peptides are highly safe. They have small molecular weight, low toxicity, and will not accumulate in the body. However, unstandardized high-dose peptide products or impure synthetic peptides may cause mild discomfort.
- What are the common applications of peptides?
Answer: Peptides are widely used in multiple fields. In biomedicine, they are made into therapeutic drugs for endocrine and immune diseases; in cosmetics, they are used for anti-aging and skin repair; in health products, they serve as nutritional supplements to improve physical fitness.
- Can the human body absorb exogenous peptides directly?
Answer: Yes. Unlike proteins that need to be decomposed before absorption, small-molecule peptides can be directly absorbed by the intestinal tract and skin with high absorption rate and utilization efficiency, and can quickly exert biological effects in the body.
- What are synthetic peptides used for?
Answer: Synthetic peptides are artificially customized amino acid chains. They are mainly used for scientific research, clinical drug development, targeted skin care ingredient production, and precise nutritional supplementation, with higher purity and targeted activity than some natural peptides.
- Do peptide products have side effects?
Answer: Standard peptide products have almost no obvious side effects for most people. Individual groups may experience mild gastrointestinal discomfort or skin sensitivity due to physical differences or excessive intake. Long-term excessive use may disrupt the body’s metabolic balance.
- What is the difference between collagen peptides and ordinary peptides?
Answer: Collagen peptides are a specific type of functional peptide extracted and decomposed from collagen, mainly targeting skin moisturizing, anti-wrinkle and joint care. Ordinary peptides cover a broader range with more diverse regulatory functions including immunity and metabolism, while collagen peptides have more focused skincare and anti-aging effects.
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