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When you look for research peptides for skin health and tissue improvement, you will notice GHK-Cu peptide quite often. Many beginners are puzzled by the following questions: what is GHK-Cu peptide, what is its activity in the human body, and what makes it unique among other bioactive peptides. The name stands for Glycyl-L-Histidyl-L-Lysine Copper, which is a naturally produced small peptide-copper complex that has become widely known in the field of cosmetic and nutrition science. The first samples of this compound were received from human plasma decades ago, and researchers have been studying its biological properties ever since. It should be mentioned that GHK-Cu is used for lab research only. This article is written for informational purposes only and does not provide medical advice.
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The GHK-Cu peptide is formed when the GHK tri-peptide is attached to a copper ion. Copper is an important trace element that participates in many enzymatic reactions responsible for antioxidant function and tissue regeneration. GHK-Cu acts as a carrier, which allows delivering copper into the cells. As we age the natural concentration of GHK in human plasma decreases, and therefore scientists are interested in knowing the effects of its supplementation with GHK-Cu peptide on the natural processes of body renewal. Unlike some other peptides that are aimed at specific metabolic functions, GHK-Cu is mainly involved in balancing the inflammatory response, extracellular matrix condition, and enhancement of antioxidant protection.
One of the areas of GHK-Cu research is skin health.In preclinical tests, GHK-Cu appeared to be valuable in how it controls the release of collagen and elastin which are important building proteins of skin making it elastic and firm. With age and environmental influence, the levels of collagen and elastin in the dermal matrix declines resulting in sagging and wrinkles. GHK-Cu can help your fibroblasts work normally and aid the skin regeneration process. In addition, GHK-Cu has antioxidant properties helping neutralize free radicals preventing them from harming skin cells and enhancing aging.
In addition to its function in skin health, GHK-Cu is studied for its effect on soft tissues. It helps regulate the inflammatory process in the tissues thereby achieving the optimal response and avoiding overreacting and prolonged inflammation. The phenomenon of healthy inflammation is crucial for tissue repair, while uncontrolled inflammation can prevent recovery from taking place. Preclinical studies reveal that GHK-Cu can stimulate angiogenesis which is the formation of new microvessels supplying blood and nutrients to the injured area.
Another thing that GHK-Cu can do is acting as an activator of oxidative stress. Free radicals produced due to such common reasons as lack of sleep and irritants from the environment destroy cell membranes as well as DNA. The copper-peptide complex restores the ability of the body to cope with oxidative damage and resist it. Such a protective mechanism does not work only for skin but also has a systemic character and is being studied on basis of cell and animal experiments.
Many people confuse GHK-Cu with other well-known peptides such as BPC-157. Although both belong to in the category of biologically active peptides, their purposes differ from each other. BPC-157 is generally studied in relation to the recovery of the digestive system and tendon tissues. On the contrary, GHK-Cu is recognized primarily as a skin-related peptide and as a molecule stimulating elastin production.
The importance of proper use of GHK-Cu cannot be overstated. GHK-Cu has not obtained a drug status allowing to use it for curing or treating any diseases. Therefore, the majority of existing studies on GHK-Cu are know-about animal ones only and this therapy has not been tested on humans yet. Anyone interested in conducting research with the help of GHK-Cu must not increase its dose for the purpose of achieving results.